Given its high sensitivity and negative predictive value, French researchers…Read more on AuntMinnie.comRelated Reading:
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The objective of this study was to investigate the association of ROCK2 expression with clinicopathological features and overall survival of breast cancer patients. MATERIAL AND METHODS The expression of ROCK2 in breast cancer and paired adjacent normal tissues was detected and compared by immunohistochemical staining of tissue array. ROCK2 mRNA expression and clinicopathological information was extracted from the TCGA breast cancer dataset. The association of ROCK2 expression with the clinicopathological characteristics of patients with breast cancer was evaluated using univariate and multivariate Cox proportional hazards…

CONCLUSIONS Expression of the YPEL3 gene was upregulated in human colonic adenocarcinoma tissue, and also inhibited the proliferation, migration, and invasion of colonic adenocarcinoma cells in vitro by inactivating the Wnt/β-catenin signaling pathway.
PMID: 29988027 [PubMed – in process]

ConclusionsExposure to levels of fluoride twice as high than the optimum in the drinking water increases the prevalence of fluorosis, dramatically decreases dental caries, and does not increase the risk of cancer, cardiovascular events, and asthma.

Chem. Commun., 2018, Advance Article DOI: 10.1039/C8CC01795F, CommunicationWeiqi Zhang, Ching-Hsuan Tung Inspired by cisplatin’s deactivation by glutathione (GSH) in cancer, a GSH responsive nanogel loaded with doxorubicin (Dox) was prepared using hyaluronan as a matrix and cisplatin as a crosslinker. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry

About one in five people are diagnosed with some form of skin cancer in their lifetime, and 100,000 Americans will be diagnosed with malignant melanoma, the most dangerous kind, in 2018.

Many discoveries now revolutionizing the prevention and treatment of cancer can be traced back to Dartmouth—including immunotherapies for solid tumors, the integration of palliative care with cancer care, and the identification of cancer risks from environmental toxins and behaviors.

Source: News at Dartmouth Medical SchoolCategory: Hospital Management Authors: Tags: Donor Impact Insider News Research campaign cancer Home-feature Interaction Norris Cotton Cancer Center Source Type: news

Publication date: June 2018Source: American Journal of Kidney Diseases, Volume 71, Issue 6Author(s): Nelly M. Cruz, Benjamin S. FreedmanCRISPR is a nuclease guidance system that enables rapid and efficient gene editing of specific DNA sequences within genomes. We review applications of CRISPR for the study and treatment of kidney disease. CRISPR enables functional experiments in cell lines and model organisms to validate candidate genes arising from genetic studies. CRISPR has furthermore been used to establish the first models of genetic disease in human kidney organoids derived from pluripotent stem cells. These gene-edi…

While the decision means the lawsuits can move forward, the judge noted that it could be a “daunting challenge” to convince him to allow a jury to hear testimony that glyphosate was responsible for individual cancer cases, the AP reported.

Source: WebMD HealthCategory: Consumer Health News Source Type: news

Conclusion The patient-based sensitivity, specificity and accuracy of WB MRI including DWI were comparable with those of PET/MRI. On the other hand, the lesion-based sensitivities of WB MRI were relatively low, mainly because of the low detectability of small lymph node metastasis. The combination of T2WI and DWI showed acceptable detectability; however, the T1WI sequence showed no additional value to detect malignant lesions on both lesion- and patient-based sensitivities.

Source: Journal of Nuclear MedicineCategory: Nuclear Medicine Authors: Tags: Other Solid Tumors Posters Source Type: research

Prostate-specific membrane antigen (PSMA) PET/CT scans can help identify prostate…Read more on AuntMinnie.comRelated Reading:
FDG-PET/CT could improve treatment for NSCLC patients
FDG-PET/CT contributes to anal cancer follow-up
AI algorithm can classify bone lesions on PET/CT images
FDG-PET/CT foretells melanoma therapy response
New PET tracer could work well for prostate cancer

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