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Find out about the latest advances that are shaping the future of Wilms’ tumor management. Therapeutic Advances in Urology

Source: Medscape Today HeadlinesCategory: Consumer Health News Tags: Hematology-Oncology Journal Article Source Type: news

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Pediatric Blood&Cancer, EarlyView.

Source: Pediatric Blood and CancerCategory: Cancer & Oncology Authors: Source Type: research

In conclusion, Pax8/Pax2 and NGFR are sensitive markers for the diagnosis of WT and CCSK, respectively. However, their specificity is limited by variable reactivity within a subset of other renal neoplasms.

Acquired von Willebrand syndrome (AVWS) is a rare acquired bleeding disorder that resembles von Willebrand disease by its clinical symptoms and laboratory findings, but differs by its negative personal and family history of bleeding diathesis. AVWS is mostly seen in the elderly, but it has been described in children, often in those with congenital heart disease and Wilms tumor. It is most commonly associated with lymphoproliferative, myeloproliferative, cardio-vascular, or autoimmune diseases, solid tumors, and certain drugs.

Source: Transfusion and Apheresis ScienceCategory: Hematology Authors: Source Type: research

International Journal of Cancer,Volume 0, Issue ja, -Not available-.

Source: International Journal of CancerCategory: Cancer & Oncology Authors: Source Type: research

Authors: Morimoto S, Fujiki F, Kondo K, Nakajima H, Kobayashi Y, Inatome M, Aoyama N, Nishida Y, Tsuboi A, Oka Y, Nishida S, Nakata J, Hosen N, Oji Y, Sugiyama H
Abstract
Adoptive T-cell therapy with T cell receptor (TCR) -engineered T cells is an attractive strategy for cancer treatment and the success in this therapy is dependent on the functional avidity of the transduced TCRs against targeted tumor antigens. Therefore, the establishment of the methodology of the efficient and precise evaluation of TCR functional avidity has been awaited. Here, we show a novel platform cell line, named 2D3, which enables the fun…

Source: OncotargetCategory: Cancer & Oncology Tags: Oncotarget Source Type: research

Wilms tumor is the most common renal tumor of childhood. Duplication of the inferior vena cava is an uncommon anomaly. In the present study, we present a case of Wilms tumor with the inferior vena cava duplica…

Source: BMC UrologyCategory: Urology & Nephrology Authors: Tags: Case report Source Type: research

Pediatric Blood&Cancer, EarlyView.

Source: Pediatric Blood and CancerCategory: Cancer & Oncology Authors: Source Type: research

Conclusions 3D reconstruction and the full-scale printing models are a useful tool in cases of complex tumor resections as they contribute to a better understanding of the relationships between the tumor and adjacent organs, helping to anticipate certain surgical complications. They also provide additional information to conventional imaging tests, being able to influence therapeutic decisions and facilitate the understanding by the family, improving doctor–patient communication. […] Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstrac…

Source: European Journal of Pediatric Surgery ReportsCategory: Surgery Authors: Tags: Case Report Source Type: research

Authors: Louati S, Senhaji N, Chbani L, Bennis S
Abstract
Ewing sarcoma/primitive neuroectodermal tumor (Ewing/PNET sarcomas or EPS) are a group of round cell tumors. Malignant round cell tumors form a large and diverse group that includes rhabdomyosarcoma, synovial sarcoma, non-Hodgkin’s lymphoma, neuroblastoma, hepatoblastoma, Wilm’s tumor, desmoplastic small round cell tumor, and other morphologically similar entities. Differential diagnosis of Ewing sarcoma/primitive neuroectodermal tumor (Ewing/PNET sarcomas or EPS) is difficult. In addition to morphology and immunohistochemistry (IHC), differential diagnosis …

Source: Disease MarkersCategory: Laboratory Medicine Tags: Dis Markers Source Type: research

Publication date: Available online 10 October 2018Source: Medical Journal Armed Forces IndiaAuthor(s): V. Manu, Tin Aung Hein, Dibyajyoti Boruah, V. SrinivasAbstractBackgroundThe aim of this study was to evaluate the expression of p53, p16, Wilms tumor gene (WT1), and Mindbomb E3 Ubiquitin Protein Ligase 1 (MIB-1) index by immunohistochemical (IHC) staining in benign, low-grade, and high-grade serous ovarian tumors.MethodsForty-one cases of ovarian serous tumors were included in the study (benign serous tumor [n = 10], low-grade ovarian serous carcinoma [n = 8], and high-grade ovarian serous c…

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