(The Francis Crick Institute) Chemicals produced by vegetables such as kale, cabbage and broccoli could help to maintain a healthy gut and prevent colon cancer, a new study from the Francis Crick Institute shows.

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This study aimed to elucidate whether symptoms of low anterior resection syndrome change over time and if the correlation to quality of life is equivalent when measured at 2 time points.
DESIGN:
This prospective cohort study included measurements at 2 time points (5 years between; range, 7.1–16.1 years from surgery to second follow-up).
SETTINGS:
This multicenter study included patients from Sweden and Denmark.
PATIENTS:
Patients were included if they were ≥18 years of age and underwent curative rectal cancer surgery with either total or partial mesorectal excision.
MAIN OUTCOME MEASURES:
Outcomes were…

BACKGROUND:
The methylator pathway of colorectal carcinogenesis, characterized by CpG island hypermethylation and BRAF mutations, accounts for ≈25% of colorectal cancers. Because these cancers tend to be right sided and because DNA methylation in the right colon increases with age, we expect an increasing proportion of right-sided cancer over time. Conversely, we expect young patients (age 50 or 81 y). Patients with IBD or hereditary syndromes were excluded.
RESULTS:
A total of 497 colorectal cancers were analyzed (266 men and 231 women); 57 patients (11.5%) were ≤50 years of age. No young cancers (0/57) were…

BACKGROUND:
Disease-free survival estimated from the time of surgery does not account for the changing likelihood of survival based on time already accrued. Conditional disease-free survival is defined as the probability of remaining disease free after reaching a specific time point without recurrence.
OBJECTIVE:
The purpose of this study was to evaluate conditional disease-free survival for patients with rectal cancer who were treated by proctectomy after neoadjuvant chemoradiation.
DESIGN:
Demographics, tumor characteristics, and tumor regression scores were assessed. Three-year conditional disease-free survival …

BACKGROUND:
Colorectal cancer invading the adjacent organs/structures is detected in 5% to 20% of all surgical interventions performed for the management of colorectal cancer.
OBJECTIVE:
Our purpose is to verify the safety and feasibility of laparoscopic surgery for the treatment of locally advanced colorectal cancer invading the adjacent organs.
DESIGN:
This is a retrospective study.
SETTINGS:
The study was conducted at a single institution in Japan.
PATIENTS:
We compared the morbidity, appropriate oncological resection, and disease-free survival of laparoscopic and open multivisceral resection in patients w…

This study aimed to evaluate if Medicaid expansion improved colorectal cancer screening for minorities and low-income patients.
DESIGN:
We used the Behavior Risk Factor Surveillance System, a nationally representative health-related telephone survey, to compare colorectal cancer screening rates from 2012 to 2016 based on Medicaid expansion status. A difference-in-difference analysis was used to compare the trends.
SETTINGS:
All states were included in this survey.
PATIENTS:
Respondents aged 50 to 64 from the early expansion, 2014 expansion, and nonexpansion states were selected.
INTERVENTIONS:
Medicaid expansio…

CONCLUSIONS:
The study results support the hypothesis that cytology is a good test for the screening of anal cancer.

Publication date: Available online 6 December 2018Source: International Journal of PharmaceuticsAuthor(s): Mariano Licciardi, Cinzia Scialabba, Roberto Puleio, Giovanni Cassata, Luca Cicero, Gennara Cavallaro, Gaetano GiammonaAbstractHuman colon cancer is one of the higher aggressive solid tumors, whose high mortality, much like many other solid tumors, results from metastasis formation. To reduce this high mortality, more effective chemotherapy, allowing a specific tumor accumulation and an efficient early-stage medical imaging as well, are still needed. At this regard, stimuli-responsive nanocarriers for anticancer drug …

You cannot go wrong incorporating a lot of cruciferous vegetables, which include broccoli and brussels sprouts as well as dark leafy greens like kale and arugula, in your diet.

Source: NYT HealthCategory: Consumer Health News Authors: Tags: Vegetables Head and Neck Cancer Colon and Colorectal Cancer Lung Cancer Breast Cancer Diet and Nutrition Vitamins Dietary Supplements and Herbal Remedies Throat Prostate Gland Source Type: news



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