Methotrexate is known for its interference with some growth of body cells. Particularly with cells which reproduce faster like skin cells, cells of the bone marrow and cancerous cells. Hence, methotrexate is used for treating some kinds of cancer of skin, neck, head, breast and lungs. It is also found to be effective in treating patients suffering from rheumatoid arthritis and psoriasis.
Methotrexate for esophageal cancer and other types are given to the patients only twice or once in a week’s time as they are not to be given daily. As studies conducted on several patients who consumed them daily are known to have died in accidents largely. This makes it imperative to follow the instructions or directions mentioned on the prescription label strictly. In case of doubts patients suffering from esophageal cancer and other types of cancer can consult their doctors and clarify their doubts.
Doctors normally do not prescribe methotrexate for a longer period and in huge amounts as it can lead to life threatening or serious side effects in the lungs, immune system, bone marrow, kidnesy and liver. Patients suffering from liver disease should not consume methotrexate if when prescribed for rheumatoid arthritis or psoriasis. And should be avoided strictly during pregnancy and while breast feeding babies. If any one of the partners is taking methotrexate it is better that the couple makes use of effective types of birth control and if by accident if the partner gets pregnant it should be brought to the notice of the doctor immediately.
In order to ensure that methotrexate is not leading to any harmful side effects, the patient who is consuming it should undergo a laboratory tests at continuous and regular intervals. While doing so the liver and kidney’s functioning would also be tested. Various medicines can also interact with this medicine. Hence the doctors should be informed about the medicines used and that are being used by the patient. It includes minerals, vitamins, drugs for other diseases by other doctors, herbal supplements or products and so on.
Before prescribing methotrexate for esophageal cancer or rheumatoid arthritis or psoriasis the patient is checked for any allergies towards it and also checked if he has liver cirrhosis, liver disease of any form, alcohol addiction, anemia, leucopenia, disorder of bone marrow and many more. Doctors would also make sure that the patients or their partners are not pregnant by making them undergo pregnancy tests. It is so because methotrexate is known to produce birth defects in unborn babies.
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