Turmeric shown to improve mental health and mood in overweight participants – Japan 12-week RCT

This is according to a randomised, double-blind, placebo-controlled study conducted on middle-aged Japanese subjects to investigate the effect of turmeric extract on low-grade inflammation.

Low-grade inflammation has been recognised as a state where systemic inflammatory mediators are only slightly elevated relative to the levels seen in acute inflammation.

This type of inflammation is considered to be related to ageing, obesity, and an unhealthy lifestyle, and potentially associated with an increased risk of metabolic syndrome, Alzheimer’s disease, mood disturbance, cancer, and mortality.

While hot water and supercritical carbon dioxide extracted turmeric has shown anti-inflammatory activities in animal studies, its effect on inflammation and general health conditions in humans is not clearly understood.

So researchers from House Wellness Foods Corporation’s Research & Development Institute carried out this study which is published in Nutrition Journal​.

Results suggest that daily intake of a mixture of a hot water extract and supercritical carbon dioxide extract of turmeric may have the potential to improve mental health and negative mood state by reducing chronic low-grade inflammation​.”

House Wellness Foods is a Japanese firm manufacturing rice, seasoning, foods, confectionery, beverages, food additives, health foods, pet foods, and pharmaceuticals.


This study recruited 90 men and women between 50 to 69 years old who were overweight, identified as a body mass index ≥ 23 to < 30 kg/m2​.

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