Want to lose weight?Diet drinks may not be a sweet spot: research


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Synthetic aftertaste may not be the only side effect of switching to diet soda, especially if you are trying to lose weight.

Drinks containing man-made objects sweetener Sucralose may increase food cravings and appetite in women and obese people, according to a new study led by researchers at the Keck School of Medicine at USC.

Just published in JAMA network openThis study is one of the largest studies to date to investigate the effects of artificial sweeteners, also known as non-nutritive sweeteners (NNS). Brain activity Appetite response in different segments of the population.

Artificial Sweets: Controversial Topics

Currently, over 40% of adults in the United States use NNS as a calorie-free way to satisfy their sweet teeth and, in some cases, achieve their weight loss goals. Despite their prevalence, the health effects of artificial sweeteners remain highly controversial and there is no clear consensus on their effects on appetite, glucose metabolism and body weight.

“There is controversy over the use of artificial sweeteners because many people use artificial sweeteners to lose weight,” said Kathleen Page, MD, a responding author of the study and an associate professor at Keck School of Medicine. Stated. “Some studies suggest that they may help, but others show that they may contribute to weight gain, type 2 diabetes and other metabolic disorders. ..

To study the effects of NNS, Page and her colleagues consumed 300 ml of sucrose (table sugar) sweetened drink, NNS sucralose or water sweetened drink as a control, during the course of three different visits. We studied 74 participants. In the next two hours, the researchers measured three things. Using an imaging technique called functional magnetic resonance imaging (fMRI), it is the activation of areas of the brain that cause appetite and food craving in response to photographs of high-calorie foods such as hamburgers and donuts. Levels of glucose (blood sugar), insulin, and other metabolic hormones in the blood. And the amount of food consumed in the snack buffet served at the end of each session. The study group consisted of the same number of men and women identified as healthy weight, overweight, or obesity, and researchers were able to investigate potential differences between the population groups.

Artificial sweeteners can make certain people feel more hungry

Imaging studies have shown increased activity in the causative areas of the brain Thirsty for food And the appetite of both women and people who became obese after drinking a drink containing sucralose when compared to a drink containing real sugar.

The study also showed a total reduction in levels of hormones that tell the body “I’m full” after drinking a sucralose-containing beverage compared to a sucralose-containing beverage, and artificially sweetened it. Hunger suggests that beverages may not be effective in controlling.

Finally, after female participants drank drinks containing sucralose, they ate more in the snack buffet than after drinking drinks containing sucralose, but snack food intake was in male participants. There was no difference. The page recommended careful interpretation of these findings, as all participants fasted overnight prior to the study and were likely to be hungry more than usual.

“Our research is beginning to provide a background for mixed results from previous studies on the neurological and behavioral effects of artificial sweeteners,” Page said. “By studying different groups, we were able to show that women and obese people may be sensitive to artificial sweeteners. In these groups, Drinking Artificially sweetened drinks can trick the brain into making you feel hungry, which can result in the consumption of more calories. “

Additional authors of this study include Alexandra Yunker, BA, Jasmin Alves, Ph.D., Brendan Angelo, MS, Alexis DeFendis, BA, and Trevor Pickering, Ph.D. From Keck School of Medicine at USC. Dr. Shan Luo, Dr. John Monterosso From USC Dornife Faculty of Psychology.

Sugar and sweeteners — how do they affect our appetite?

For more information:
Obesity and sexual associations with different effects of sucralose vs. sucrose on appetite and reward processing, JAMA network open (2021).… tworkopen.2021.26313

Quote: Want to lose weight?Diet drinks may not be a sweet spot: Study (September 28, 2021) from September 28, 2021 Got

This document is subject to copyright. No part may be reproduced without written permission, except for fair transactions for personal investigation or research purposes. The content is provided for informational purposes only.


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