02xl is your source for accurate and trustworthy information so you can make the best choices for your health and wellness.
PS: Please note that 02xl provides this information for the benefit of the rare disease and overweight community. 02xl is not a medical provider or health care facility and thus can neither diagnose any disease or disorder nor endorse or recommend any specific medical treatments. Patients must rely on the personal and individualized medical advice of their qualified health care professionals before seeking any information related to their particular diagnosis, cure or treatment of a condition or disorder.
This is a video synopsis/summary of a Peer Exchange involving Ryan Haumschild, PharmD, MS, MBA; Tony Phillip, MD; Mrinal Gounder, MD; Ravin Ratan, MD, MEd; and Derek Van Amerongen, MD, MS.
Haumschild delves into the current standards of care and treatment landscape for desmoid tumors, referencing the National Comprehensive Cancer Network (NCCN) guidelines. Ratan emphasizes the guidelines’ strategic division of tumors into those at risk of complications and those not, promoting active surveillance for the majority. The guidelines avoid overprescription, reflecting the need for tailored, multidisciplinary approaches. Van Amerongen highlights the significance of NCCN guidelines as a gold standard, guiding health plan policies to align with the latest treatment algorithms.
Gounder details the current standard of care, emphasizing a shift from surgery to up-front watchful waiting. Individualized decision-making considers patient symptoms, tumor progression, and location. Local approaches, including high-intensity focused ultrasound and transarterial chemoembolization, complement systemic therapies such as traditional cytotoxic chemotherapies, tyrosine kinase inhibitors, and γ-secretase inhibitors. Clinical trials remain crucial for exploring novel options, ensuring optimal care for rare diseases such as desmoid tumors. The discussion underscores the importance of aligning treatment decisions with NCCN guidelines, providing valuable insights for both providers and payers in managing desmoid tumors effectively.
Video synopsis is AI generated and reviewed by AJMC® editorial staff.