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Selected references
Transcriptional signatures of Itk-deficient CD3+, CD4+ and CD8+ T-cells.
Blomberg KE, Boucheron N, Lindvall JM, Yu L, Raberger J, Berglöf A, et al
BMC Genomics 2009 May;10():233
Regulation of nucleocytoplasmic shuttling of Bruton’s tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54).
Gustafsson MO, Hussain A, Mohammad DK, Mohamed AJ, Nguyen V, Metalnikov P, et al
Mol Cell Biol 2012 Jul;32(13):2440-53
Btk29A promotes Wnt4 signaling in the niche to terminate germ cell proliferation in Drosophila.
Hamada-Kawaguchi N, Nore BF, Kuwada Y, Smith CI, Yamamoto D
Science 2014 Jan;343(6168):294-7
Silencing of Bruton’s tyrosine kinase (Btk) using short interfering RNA duplexes (siRNA).
Heinonen JE, Smith CI, Nore BF
FEBS Lett 2002 Sep;527(1-3):274-8
Phosphatidylinositol-3-kinase-dependent phosphorylation of SLP-76 by the lymphoma-associated ITK-SYK fusion-protein.
Hussain A, Faryal R, Nore BF, Mohamed AJ, Smith CI
Biochem Biophys Res Commun 2009 Dec;390(3):892-6
Signaling of the ITK (interleukin 2-inducible T cell kinase)-SYK (spleen tyrosine kinase) fusion kinase is dependent on adapter SLP-76 and on the adapter function of the kinases SYK and ZAP70.
Hussain A, Mohammad DK, Gustafsson MO, Uslu M, Hamasy A, Nore BF, et al
J Biol Chem 2013 Mar;288(10):7338-50
Bruton’s tyrosine kinase (Btk): function, regulation, and transformation with special emphasis on the PH domain.
Mohamed AJ, Yu L, Bäckesjö CM, Vargas L, Faryal R, Aints A, et al
Immunol Rev 2009 Mar;228(1):58-73
Regulation of nucleocytoplasmic shuttling of Bruton’s tyrosine kinase (Btk) through a novel SH3-dependent interaction with ankyrin repeat domain 54 (ANKRD54).
Gustafsson MO, Hussain A, Mohammad DK, Mohamed AJ, Nguyen V, Metalnikov P, et al
Mol Cell Biol 2012 Jul;32(13):2440-53
Dual phosphorylation of Btk by Akt/protein kinase b provides docking for 14-3-3ζ, regulates shuttling, and attenuates both tonic and induced signaling in B cells.
Mohammad DK, Nore BF, Hussain A, Gustafsson MO, Mohamed AJ, Smith CI
Mol Cell Biol 2013 Aug;33(16):3214-26
Differential evolutionary wiring of the tyrosine kinase Btk.
Nawaz HM, Kylsten P, Hamada N, Yamamoto D, Smith CI, Lindvall JM
PLoS One 2012 ;7(5):e35640
The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells.
Raberger J, Schebesta A, Sakaguchi S, Boucheron N, Blomberg KE, Berglöf A, et al
Proc Natl Acad Sci U S A 2008 Nov;105(46):17919-24
Single-stranded DNA oligonucleotides inhibit TLR3-mediated responses in human monocyte-derived dendritic cells and in vivo in cynomolgus macaques.
Sköld AE, Hasan M, Vargas L, Saidi H, Bosquet N, Le Grand R, et al
Blood 2012 Jul;120(4):768-77
The Tec family of cytoplasmic tyrosine kinases: mammalian Btk, Bmx, Itk, Tec, Txk and homologs in other species.
Smith CI, Islam TC, Mattsson PT, Mohamed AJ, Nore BF, Vihinen M
Bioessays 2001 May;23(5):436-46
The gene involved in X-linked agammaglobulinaemia is a member of the Src family of protein-tyrosine kinases. 1993.
Vetrie D, Vořechovský I, Sideras P, Holland J, Davies A, Flinter F, et al
J Immunol 2012 Apr;188(7):2948-55
Proteasome-dependent autoregulation of Bruton tyrosine kinase (Btk) promoter via NF-kappaB.
Yu L, Mohamed AJ, Simonson OE, Vargas L, Blomberg KE, Björkstrand B, et al
Blood 2008 May;111(9):4617-26
Regulation of Bruton tyrosine kinase by the peptidylprolyl isomerase Pin1.
Yu L, Mohamed AJ, Vargas L, Berglöf A, Finn G, Lu KP, et al
J Biol Chem 2006 Jun;281(26):18201-7